Human dermal absorption of chlorinated organophosphate flame retardants; implications for human exposure
نویسندگان
چکیده
منابع مشابه
Brominated and Chlorinated Flame Retardants
1International POPs Elimination Network, Berkeley, California, USA; 2Department of Chemistry, University of California, Berkeley, California, USA; 3Green Science Policy Institute, Berkeley, California, USA; 4Department of Materials and Environmental Chemistry, and 5Department of Applied Environmental Science, Stockholm University, Stockholm, Sweden; 6Lawrence Berkeley National Laboratory, Berke...
متن کاملEvaluation of 3D-human skin equivalents for assessment of human dermal absorption of some brominated flame retardants.
Ethical and technical difficulties inherent to studies in human tissues are impeding assessment of the dermal bioavailability of brominated flame retardants (BFRs). This is further complicated by increasing restrictions on the use of animals in toxicity testing, and the uncertainties associated with extrapolating data from animal studies to humans due to inter-species variations. To overcome th...
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We have examined several emerging brominated flame retardants (BFRs) including 2-ethyl-1-hexyl-2,3,4,5-tetrabromobenzoate (TBB), bis(2-ethylhexyl) tetrabromophthalate (TBPH), 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE), 4,5,6,7-tetrabromo-1,1,3-trimethyl-3-(2,3,4,5-tetrabromophenyl)-indane (OBIND), and decabromodiphenyl ethane (DBDPE) in paired human maternal serum (n = 102) and breast milk (...
متن کاملHuman exposure to new Brominated Flame Retardants (BFRs)
Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium Division of Environmental Health and Risk Management, School of Geography, Earth, and Environmental Sciences, University of Birmingham, Birmingham, B15 2TT, UK The Centre for Environment, Fisheries and Aquaculture Science, CEFAS Lowestoft Laboratory, Pakefield Road, Lowestoft, Suffolk NR33 0HT, UK Norwegian...
متن کاملDermal uptake and percutaneous penetration of ten flame retardants in a human skin ex vivo model.
The dermal uptake and percutaneous penetration of ten organic flame retardants was measured using an ex vivo human skin model. The studied compounds were DBDPE, BTBPE, TBP-DBPE, EH-TBB, BEH-TEBP, α, β and γ-HBCDD as well as syn- and anti-DDC-CO. Little or none of the applied flame retardants was recovered in either type of the receptor fluids used (physiological and worst-case). However, signif...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 2016
ISSN: 0041-008X
DOI: 10.1016/j.taap.2015.12.004